![]() To reduce the incidence of paracetamol overdose, legislation was passed in the UK in 1998 to limit the number of tablets that could be bought in one purchase: 16 tablets at present (up to 32 tablets in pharmacies). Paracetamol poisoning is the most common cause of acute liver failure (ALF). In an English GP study, it featured as the most common agent of self-harm among 10- to 24-year-olds. This represents an 11% increase from the previous year. In England and Wales, there were 219 deaths from poisoning by paracetamol and its compounds in 2016. In the UK it is one of the most common agents of intentional self-harm. ![]() It is normally found as a 500 mg tablet but it is often combined with other active ingredients in various preparations. It is a very useful analgesic (alone or in combination) and also is an antipyretic. It is widely prescribed and cheap to buy over the counter, making it a common drug taken in overdose. Paracetamol is widely available and has been around since the 1950s. Synonyms: acetaminophen poisoning Background
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